Bruceine D
Bruceine D
CAS: 21499-66-1
Molecular Formula: C20H26O9
Bruceine D - Names and Identifiers
Bruceine D - Physico-chemical Properties
| Molecular Formula | C20H26O9 |
| Molar Mass | 410.42 |
| Density | 1.60 |
| Melting Point | 294-295℃ |
| Boling Point | 661.3±55.0 °C(Predicted) |
| Specific Rotation(α) | -21 (Py) |
| Solubility | DMSO : 100 mg/mL (243.65 mM; Need ultrasonic) |
| Appearance | White crystal or powder |
| pKa | 11.55±0.70(Predicted) |
| Storage Condition | 2-8°C |
| MDL | MFCD00221753 |
| Physical and Chemical Properties | White crystalline powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Brucea javanica fruit. |
| Use | Brucea javanica D has the effects of treating malignant tumors, antimalarial and anti-inflammatory. Used for content determination/identification/pharmacological experiment, etc. |
Bruceine D - Reference
| Reference Show more | 1. Zheng Ying, Wang gangyang, Chen Ruiling, et al. To investigate the effects of bruceanin D on proliferation, apoptosis and autophagy of osteosarcoma cells [J]. Chinese Journal of Bone and Joint, 2017, 06(v.6):38-43. 2. Pan, Fei-Yun Zheng, Haiyan, et al. Effect of brucea javanica D on HPV16 infected cell lines and its possible mechanism [J]. Journal of Wenzhou Medical University, 2015, 3 (2):89-94. 3. Zhang, Yining, et al. "Development and validation of a sensitive LC-MS/MS assay for quantification of bruceine D in rat plasma." Biomedical Chromatography 30.11 (2016): 1873-1876.https:// doi.org/10.1002/bmc.3724 4. Wang, Shangyu, et al. "Bruceine D inhibits tumor growth and stem cell‐like traits of osteosarcoma through inhibition of STAT3 signaling pathway." Cancer medicine 8.17 (2019): 7345-7358.https://doi.org/10.1002/cam4.2612 5. [IF=1.902] Yining Zhang et al."Development and validation of a sensitive LC-MS/MS assay for quantification of bruceine D in rat plasma."Biomed Chromatogr. 2016 Nov;30(11):1873-1876 6. [IF=3.357] Shangyu Wang et al."Bruceine D inhibits tumor growth and stem cell‐like traits of osteosarcoma through inhibition of STAT3 signaling pathway."Cancer Med-Us. 2019 Dec;8(17):7345-7358 |
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Product Name: Bruceine D Visit Supplier Webpage Request for quotationCAS: 21499-66-1
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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